Chronic and recurrent mental health problems are often not just a challenge to the patient but also to the therapist, as these severe conditions frequently defy standard treatment approaches. Many of the Axis I disorders (depression, anxiety, OCD, PTSD, somatoform disorders, addictions and diffuse psychiatric complaints) have a high risk of becoming chronic conditions that eventually wear out the patient and the treatment providers. Standard CBT treatments that aim at symptom reduction often fail to address the maintaining factors that relate to the intra-psychic dynamics of personality functioning. The workshop addresses this gap by utilizing an integrative approach of evidence-based therapies (ranging from CBASP to Schema Therapy to psychodynamic approaches e.g. TFP, MBT) that focuses on personality functioning as an underlying factor in maintaining chronic mental health disorders. It aims to refine therapists’ conceptualization of these complex cases and to enhance their repertoire of interventions based in a clear understanding of the patients’ pathology.